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Bacterial and Eukaryotic Porins: Structure, Function, Mechanism, Chapter 16: Function of the Outer Mitochondrial Membrane Pore (Voltage-Dependent Anion Channel) in Intracellular Signalingкнига
- Авторы: Roland Benz Prof Dr, Mikhail Vyssokikh, Dieter Brdiczka
- Год издания: 2005
- Место издания: Provider John Wiley, Sons Weinheim, FRG
- Объём: 366 страниц
- ISBN: 9783527307753
- DOI: 10.1002/3527603875
- Аннотация: Keywords: function of the outer mitochondrial membrane pore in intracellular signaling; structure and isotypes of VDAC; influence of phospholipids on VDAC structure; VDAC conductance and ion selectivity; porins as specific binding sites; cytochrome c; VDAC–ANT complexes Summary This chapter contains sections titled: Introduction Structure and Isotypes of VDAC The Influence of Phospholipids on VDAC Structure VDAC Conductance and Ion Selectivity Physiological Significance of the Voltage Dependence Porins as Specific Binding Sites VDAC senses Inner Membrane Functions in the Contact Site Cytochrome c is a Component of the Contact Sites Isolation and Characterization of VDAC–ANT Complexes Reconstitution of VDAC–ANT Complexes Importance of Metabolic Channeling in Regulation of Energy Metabolism The VDAC–ANT Complex as Permeability Transition Pore The VDAC–ANT Complex as a Target for Bax-dependent Cytochrome c Release The VDAC–ANT Complexes contain Cytochrome c The Importance of the Kinases in Regulation of Apoptosis Suppression of Bax-dependent Cytochrome c and Permeability Transition by Hexokinase Suppression of Permeability Transition by Mitochondrial Creatine Kinase
- Добавил в систему: Высоких Михаил Юрьевич